hrp0089p2-p108 | Diabetes & Insulin P2 | ESPE2018

Severe Stress-Induced Subcutaneous and Intravenous Insulin Resistance in an Eight Year Old Boy with T1DM, Necessitating Seven Months of IV Insulin, Reversed after Psychiatric Treatment

Ommen CCN van , Hoorweg-Nijman JJG , Stuart H , Deschamps PKH , Stuart AA Verrijn

Background: Persistent severe insulin resistance (IR) in T1DM is infrequent, complex to handle and disabling. Genetic and epigenetic factors play a significant role in the pathophysiology of IR. This case report discusses the potential role of habitual and stress-inducing environmental factors in a school-aged boy with a neurodevelopmental disorder.Case report: We present an eight year old boy with a three year history of T1DM (GAD positive) regulated by...